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Answer length: the prompt instructs exhaustiveness, and the document budget should be per-caller

Status: Open.

#172 In reactome/reactome_chatbot;

· adamjohnwright opened on Sep 4, 2026

Retrieval: replace SelfQueryRetriever with a plain semantic retriever?

Status: Open.

#171 In reactome/reactome_chatbot;

· adamjohnwright opened on Sep 4, 2026

Retrieval: BM25 and vector results are concatenated, not fused

Status: Open.

#170 In reactome/reactome_chatbot;

· adamjohnwright opened on Sep 4, 2026

Retrieval: golden-output harness for judging retriever changes

Status: Open.

#168 In reactome/reactome_chatbot;

· adamjohnwright opened on Sep 4, 2026

Multiple failures with small LLM (Ollama)

Status: Open.

#160 In reactome/reactome_chatbot;

· Ehsanstp opened on Apr 26, 2026

Bug: asyncio.run() in __del__ causes RuntimeError crash in production

Status: Open.

#154 In reactome/reactome_chatbot;

· bleedblack1 opened on Mar 15, 2026

feat: implement multi-hop pathway traversal for deeper mechanistic reasoning

Status: Open.

#152 In reactome/reactome_chatbot;

· bhavyakeerthi3 opened on Mar 15, 2026

bug: AgentGraph hardcodes LLM and embedding models — ignores YAML configuration

Status: Open.

#148 In reactome/reactome_chatbot;

· bhavyakeerthi3 opened on Mar 15, 2026

bug: asyncio.run() inside AgentGraph destructor triggers RuntimeError and leaks connections

Status: Open.

#146 In reactome/reactome_chatbot;

· bhavyakeerthi3 opened on Mar 14, 2026

bug: flow_context key missing from CrossDatabaseState — topology data silently lost between nodes

Status: Open.

#145 In reactome/reactome_chatbot;

· bhavyakeerthi3 opened on Mar 14, 2026

feat: support causal chain queries for mechanistic biological reasoning

Status: Open.

#143 In reactome/reactome_chatbot;

· bhavyakeerthi3 opened on Mar 13, 2026

feat: route questions to RAG or MCP tools based on query intent

Status: Open.

#141 In reactome/reactome_chatbot;

· GovindhKishore opened on Mar 12, 2026